Read labels on paints and mediums - some are mildly toxic (cadmium colors) -Avoid eating or smoking while you paint -Wash hands thoroughly after painting session; try applying lotion to hands before hand, paints will wash off easier -Some solvents don't produce deadly fumes, however, should be used in well ventilated room - open a window -Some solvents are flammable and toxic (gasoline, kerosene) - stick to turpentine and petroleum products made for artist's use.