Macke was educated at the Kreuzgymnasium (1897-1900) and became a friend of Hans Thuar, who would also become an artist.
When he was thirteen, the family moved to Bonn, where Macke studied at the Realgymnasium and became a friend of Walter Gerhardt and Gerhardt's sister, Elisabeth, whom he would marry a few years later. The first artistic works to make an impression on the boy were his father's drawings, the Japanese prints collected by his friend Thuar's father and the works of Arnold Bocklin which he saw on a visit to Basel in 1900.